Episode 07.01.2026 - Top 20 Drugs: Diabetes
SUMMARY
Metformin, sold under the brand name Glucophage, was the ninth most prescribed drug in America in 2025 and the only diabetes medication to land in the top 20. In this episode, Dr. Bryan Ardis walks through the published package insert and FDA black box warning that most patients never read, including metformin-associated lactic acidosis, which is fatal in roughly half the cases it occurs, chronic diarrhea reported in 53 percent of users, and the steady depletion of heart-protective vitamin B12.
He then lays out the peer-reviewed research on natural compounds shown to lower blood sugar, improve insulin sensitivity, and protect the liver, kidneys, and pancreas from the very damage these drugs can cause. With an estimated 500 million diabetics worldwide today, this is essential viewing for anyone you love who is managing type 2 diabetes.
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Guggul Resin Extract – the episode's hero nutrient, studied to improve blood sugar control, increase glycogen storage, and shield the liver, kidneys, and pancreas from drug-induced damage.
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D3+K2 Organic – vitamin D3 and K2 suspended in organic MCT oil, shown in clinical trials to significantly reduce blood glucose and improve insulin resistance while supporting bone density.
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Bio-Active Copper – Cuprous Nicotinic Acid (Cu1) linked in research to better glycemic control, antioxidant defense, and healthy kidney function.
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Foreign Protein Cleanse – featuring organic licorice root and cinnamon, both researched to lower fasting blood sugar and enhance insulin signaling.
TAGS
The Dr. Ardis Show, Dr. Bryan Ardis, Top 20 Drugs, Metformin, Glucophage, Type 2 Diabetes, Blood Sugar, Insulin Resistance, Lactic Acidosis, Guggul Resin, Vitamin D3 K2, Bioactive Copper, Foreign Protein Cleanse, Licorice Root, Cinnamon, Glycemic Control, Natural Medicine, Root Cause Healing, Functional Medicine, Holistic Health